Primordial germ cell (PGC) specification occurs early in development.PGC specifiers have been identified in Drosophila, mouse, and human but remained elusive in most animals.Here we identify the RNA-binding protein Dnd as a critical PGC specifier in the medaka fish (Oryzias latipes).Dnd depletion specifically abolished PGCs, and its overexpression
Rudolf Engelhard presents a lesson model in his article How to Deal with Party Politics at School? Furniture: Island that dates back to the 1960s, when civic education was revived in the Federal Republic of Germany (West-Germany).In order to improve civic education at school, the former Ministers of Education of German states reached a joint decisi
Abstract Background This study aimed to assess the feasibility and acceptability of an oral health self-care e-learning intervention for overseas workers as well as the research procedures for a future controlled trial.Methods We randomly allocated participants to either the intervention (n = 48) or control (n = 51) group.The intervention group rec
Fargesin is a bioactive lignan from Flos Magnoliae, an herb widely used in the treatment of allergic rhinitis, sinusitis, and headache in Asia.We sought to investigate whether fargesin ameliorates experimental inflammatory bowel disease (IBD) in mice.Oral administration of fargesin significantly attenuated the symptoms of dextran sulfate sodium (DS